Top Definition
to give in to one's sexual urges in a quick manner; usually referring to females
dang i was with abby for 10 mintes when she was ready to give it up!
بواسطة the give it upper مارس/آذَار 2, 2004
to cheer for someone, or what they bring to the game
Give it up to your dj on the 1-2s keepin it crunk for the party
بواسطة DJ Kayla فبراير/شباط 29, 2004
A request for praise which can be issued either by the recieving party or a third party.
Give it up for my man DJ Mike!
بواسطة Majik Fox فبراير/شباط 28, 2004
To cease efforts now otherwise pointless
"Just give it up man, she's not interested in you."

"You'd better give it up, unless you're rollin' for a bitch-slap."
بواسطة Krispy فبراير/شباط 29, 2004
give sex to
You're not getting your money till you give it up.
بواسطة Anonymous يونيو/حَزيران 16, 2002
to give in to temptation
"Yo mane, that hizzo is expecting some chedda if she be givin it up
بواسطة MC Rizzle مارس/آذَار 3, 2004
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