The act of throwing someone or something out of a window.
Helga: "What did you just do Bobby?!"
Bobby: "What can't I defenestrate my trash out on to the highway?"
Helga: "Are you retarded?! That's called littering, we could be fined!"
(Cue the police)
بواسطة Painthetownfred فبراير/شباط 2, 2010
the defensive act of castrating someone in order to prevent sexual advances. First used in Questionable Content comic number 36.
I had to defenestrate my roommate before he tried to sleep with me.
بواسطة RoblingRobot نوفمبر/تشرين الثّاني 10, 2009
to reduce to utter ruin or nonexistence; destroy utterly; to molliwhop something real nice
After the Mark made a comment about Sean's sister, Sean defenestrated him. Mark was last seen missing two teeth and with a nice shiner.
بواسطة Soheil Saeed فبراير/شباط 26, 2008
To quickly close a computer window so as to prevent your boss/girlfriend/etc. from seeing it.
I was checking out some hot girl on girl porn on the internet when my girl suddenly came home and I had to defenestrate it right quick.
بواسطة Windoze XP مارس/آذَار 25, 2005
To uninstall software from a Microsoft operating system, usually in frustration.
I couldn't get that program to do what I needed it to, so I defenestrated it and installed something better.
بواسطة jsgarvin سبتمبر/أيلول 23, 2010

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