God be with you, general wishes of well being be upon you.
'blessup yo' self foo'
بواسطة Psyda يوليو/تمُّوز 28, 2008
Top Definition
A greeting of spiritual affirmation between friends - can be used in form of "Hello" or "Goodbye".
"Bless up, brother"
"hey hey, what's going on?"

or

"See you tomorrow, mate"
"Bless up"
بواسطة VBR213 أكتوبر/تشرين الأوّل 10, 2009
DJ Khaled a spiritual leader uses this term to indicate his thankfulness to god. It can be used as greetings, after hearing good or bad news. The meaning is not quite clear but it's usage is. Bless up.
Random Dude:Yo! Star wars just came out :D
Major DJ Khaled Fan: Bless Up
بواسطة Lord Vignesh إبريل/نَيْسان 16, 2016
A term used by celebrity DJ Khaled in order to show reverence to God, or give gratitude to what he has given to you in an opportunity. Also used after hearing something nice, greeting friends, or randomly interjecting statements.
Random Kid: I got an A on the final
DJ Khaled Follower: Bless Up, LIOOON.
بواسطة Lord Vignesh إبريل/نَيْسان 21, 2016
A retard's way of saying "God Bless you." because their brain has a lower processing power than a potato.
Man 1: Hey, how's it going?
Man 2: Bless Up! Heh, YOLO man!
بواسطة D33tly إبريل/نَيْسان 14, 2016

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