When type 1 and 2 diabetics have a blood sugar level that is above the respected 120 mark.
Also, can be a state of being in which some type 1 diabetics experience when a crazy high bloodsugar level is contradicted with a large dose of sweet insulin. The celestial hormone thus opens the path for excessive amounts of built-up sugar in the bloodstream to bodily cells, kind of like a large dam exploding in a granduer fashion. The pent up sugar then proceeds unto releasing one metric shit ton of energy to the afflicted person. This natural hightened mental/physical state is when a diabetic's best works are done and most memorable memories are made.
Dude1: Has (insert diabetic's name here) been drinking or sometning? He's sofa king crazy right now!
Dude2: I think so, I saw him shooting up with something before...
Dude1: Oh, so he must have a diabetic high right now.
Dude2: Sweet, let's find him some more carbohydrates.